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This Concept Map, created with IHMC CmapTools, has information related to: CBL A1 Metabolic Syndrome, insulin resistance phosphorylation of glycogen phosphorylase (inactivated), TAG degredation from VLDL and chylomicrons manifests as increased serum TAG levels, fasted state triggers increased glucagon, acetyl coA activates gluconeogenesis, insulin resistance phosphorylation of glycogen synthase (activated), insulin dephosphorylation of glycogen synthase (activated), insulin resistance leads to interference in normal intracellular signaling cascade response to insulin, insulin by beta cells in pancreas, stored TAG in adipose tissue degraded into glycerol, glucagon phosphorylation of glycogen phosphorylase (inactivated), beta cells in pancreas leading to dysfunction, glycerol used by liver for gluconeogenesis, increased serum free FA levels taken up by liver where it undergoes either TAG synthesis, stored TAG in adipose tissue degraded into fatty acids, insulin resistance leads to overproduction of insulin, beta oxidation producing acetyl coA, gluconeogenesis contributing to increased serum glucose levels, glucagon phosphorylation of glycogen synthase (activated), insulin dephosphorylation of glycogen phosphorylase (inactivated), insulin dephosphorylation of glucose 1,6-biphosphatase 2 (favors glycolysis when dephosphorylated favors GNG when phosphorylated)