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Deze Concept Map heeft informatie gerelateerd aan: klaar, M-Cdk + Cdc25, Fc-gamma-R Src, LYN P, Mitochondrium scheidt uit Cytochroom c, Actief caspase 9 Caspase 3,6,7, P53 BCL-XL/BCL2, smad 2/3 E2F4/5 p107 complex c-Myc, G1-Cdk +++ G1, Groeifactoren: -EGF -PDGF -FGF -HGF -IGF-1 -VEGF -NGF fosforyleert Tyrosine Kinase Receptor, E2F activeert Fos, smad 2 / smad 3 vormt smad 2/3 E2F4/5 p107 complex, PI 3-kinase activeert Akt/PKB, BH3-only PUMA Mitochondrium, G2 M, P21 cyclin E CDK2, TNF Receptor bindt DISC (complex), foxo G2, E2F Veranderingen in genexpressie, Mdm2 p53-Mdm2 complex, cyclin E CDK2 +++ G1