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This Concept Map, created with IHMC CmapTools, has information related to: Neoplastic Disorders Case Study 2, A 57-year-old man comes to the office complaining of malaise for several weeks. He says that he has not been feeling well for some time, with fatigue, depressed mood, loss of appetite. and a 20-lb unintentional weight loss. In addition, he has been bothered by generalized itching of his skin and has tried moisturizing lotions and creams without improvement. He denies fevers. abdominal pain, nausea, vomiting, or diarrhea. He does think his stools have been lighter in color recently. He has no other medical history and takes no medications except for a multivitamin. He drinks alcohol occasionally and smokes cigars. On examination, he is afebrile, with heart rate 68 bpm and blood pressure 128/74 mm Hg. He has a flat affect and a somewhat disheveled appearance. He has noticeable icterus of his sclera and skin. His chest is clear, and his heart rhythm is regular without murmurs. His abdomen is soft and nontender with active bowel sounds, a liver span of 10 cm, and no splenomegaly or masses. His skin has a few excoriations on his arms and back, but no rashes or telangiectasias. Blood is obtained for laboratory analysis; the results are available the next day. His serum albumin is 3.1 g/dL, alkaline phosphatase 588 IU/L, total biliruhin 8.5 mg/dL, direct bilirubin 6 mg/dL, alanine aminotransferase (ALT) 175 IU/L, and aspartate aminotransferase (AST) 140 IU/L. His hemoglobin level is 13.5 g/dL. Prothrombin time (PT) is 15 seconds, and partial thromboplastin time (PTT) is 32 seconds. suggest What is the next step?, A 57-year-old man comes to the office complaining of malaise for several weeks. He says that he has not been feeling well for some time, with fatigue, depressed mood, loss of appetite. and a 20-lb unintentional weight loss. In addition, he has been bothered by generalized itching of his skin and has tried moisturizing lotions and creams without improvement. He denies fevers. abdominal pain, nausea, vomiting, or diarrhea. He does think his stools have been lighter in color recently. He has no other medical history and takes no medications except for a multivitamin. He drinks alcohol occasionally and smokes cigars. On examination, he is afebrile, with heart rate 68 bpm and blood pressure 128/74 mm Hg. He has a flat affect and a somewhat disheveled appearance. He has noticeable icterus of his sclera and skin. His chest is clear, and his heart rhythm is regular without murmurs. His abdomen is soft and nontender with active bowel sounds, a liver span of 10 cm, and no splenomegaly or masses. His skin has a few excoriations on his arms and back, but no rashes or telangiectasias. Blood is obtained for laboratory analysis; the results are available the next day. His serum albumin is 3.1 g/dL, alkaline phosphatase 588 IU/L, total biliruhin 8.5 mg/dL, direct bilirubin 6 mg/dL, alanine aminotransferase (ALT) 175 IU/L, and aspartate aminotransferase (AST) 140 IU/L. His hemoglobin level is 13.5 g/dL. Prothrombin time (PT) is 15 seconds, and partial thromboplastin time (PTT) is 32 seconds. suggest What is the most likely diagnosis?