Quiz - Chapter 8
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1.
Which of the following is a TRUE statement?
A.
“Allergy” means deleterious effects of hypersensitivity.
B.
“Immunity” means an altered immunologic response.
C.
“Hypersensitivity” means the protective response to an antigen.
D.
“Autoimmunity” is the normal response to foreign antigens.
2.
Which of the following is NOT one of the four distinct types of hypersensitivity reactions?
A.
Type I IgE allergic reactions
B.
Type II tissue-specific reactions
C.
Type III immune complex reactions
D.
Type IV autoimmune reactions
3.
Which of the following is a TRUE statement regarding hypersensitivity reactions?
A.
They require sensitization against a particular antigen.
B.
They occur after the primary immune response.
C.
Reactions are always delayed.
D.
The most delayed reaction is anaphylaxis.
4.
Which of the following is an accurate description of a type I reaction?
A.
It is mediated by IgA.
B.
Most type I reactions are allergic.
C.
Most occur against medications.
D.
It never contributes to autoimmune diseases.
5.
Which of the following is the term for an antibody that binds to a mast cell?
A.
Cytotropic
B.
Allergen
C.
Antigen
D.
Fc
6.
Which of the following is NOT an action of histamine?
A.
It relaxes bronchial smooth muscle.
B.
It increases vascular permeability.
C.
It causes edema.
D.
It increases blood flow into the affected area.
7.
Which of the following is FALSE regarding type I allergic responses?
A.
They can be controlled by controlling histamine.
B.
A negative feedback mechanism stops degranulation.
C.
Most of the biologic effects are due to histamine.
D.
The tissues affected in type I reactions have small concentrations of mast cells.
8.
Which of the following is NOT another name for urticaria?
A.
Rhinitis
B.
Hives
C.
Wheal/flare
D.
Dermal skin reaction
9.
Which of the following is TRUE regarding atopic individuals?
A.
If one parent has allergies, there is a 4% chance the offspring will have allergies.
B.
If two parents have allergies, there is a 50% chance their offspring will have allergies.
C.
Atopic individuals tend to produce higher quantities of IgE.
D.
There are no genes associated with an atopic state.
10.
Which of the following is NOT a mechanism of how type II hypersensitivity affects cells?
A.
The cell is destroyed by antibody and complement.
B.
Antibody may cause phagocytosis.
C.
Components of neutrophils will release their granules.
D.
Antigen-mediated cytotoxicity occurs.
11.
Which of the following is TRUE of “serum sickness”?
A.
It is caused by the formation of immune complexes in the blood.
B.
It is deposition of complexes in the blood vessels.
C.
It occurs through cytotoxic T cells.
D.
It binds antigen to the cell surface.
12.
Which of the following is NOT an example of type IV sensitivity reactions?
A.
Graft rejection
B.
Skin test for tuberculosis
C.
Arthus reactions
D.
Autoimmune processes
13.
Which of the following is TRUE regarding type IV allergic reaction?
A.
Immediate in its action
B.
Infiltrates with B cells
C.
Has a red, soft center
D.
Can be transferred by cells
14.
Which of the following is an example of alloimmune disease?
A.
Tuberculin reaction
B.
Graves' disease
C.
Contact dermatitis
D.
Penicillin allergy
15.
A woman presents with systemic lupus erythematosus (SLE). Which of the following would you expect to see?
A.
Male gender
B.
White race
C.
Arthritis
D.
Memory loss
16.
A person in the ICU has a history of a kidney transplant. Which of the following is TRUE regarding rejection?
A.
It is a type IV hypersensitivity.
B.
Hyperacute rejection is common.
C.
Acute rejection occurs within months to years.
D.
Without drugs it takes years for rejection.
17.
A person is transfused with a unit of unmatched packed RBCs. Which of the following is a TRUE statement regarding transfusion?
A.
There are only three different RBC antigens.
B.
There are 80 major carbohydrate antigens.
C.
People with O type blood have neither A or B antigens.
D.
A person with type A blood contains anti-O antibodies.
18.
A person has type AB-positive blood. Which of the following is a TRUE statement?
A.
This person produces no anti-D antibodies.
B.
This person has one genotype,
DD.
C.
This person has the
dd
genotype.
D.
About 15% of the population is Rh positive.
19.
A colleague has been stuck by a needle with blood from an HIV-infected person. Which of the following statements regarding HIV is TRUE?
A.
It is a retrovirus.
B.
It carries its genetic information in DNA.
C.
It uses reverse transcriptase to convert DNA to RNA.
D.
It uses reverse transcriptase to insert virus into infected cells.
20.
A person has AIDS. Which of the following symptoms would you NOT expect to see?
A.
Increased appetite
B.
Kaposi sarcoma
C.
Perianal vesicular and ulcerative lesions
D.
Deterioration of vision from cytomegalovirus
21.
Secondary immune deficiencies:
A.
are related to genetic defects.
B.
can be associated with psychologic stress.
C.
are associated with clinically relevant infections.
D.
are combined T- and B-cell deficiencies.
22.
Which of the following has NOT been associated with depressed immune function?
A.
Age
B.
Psychologic stress
C.
Malignancies
D.
Vaccines
Quiz - Chapter 8
Quiz - Chapter 8