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This Concept Map, created with IHMC CmapTools, has information related to: Blankenbeckler_3_score, Typical agents Primary ADR's Effects: sedative,anticholinergic extrapyramidal,movement disoders, hypotensive, Bipolar Disorders pharmacological intervention Antipsychotics Used: Olanzapine- acute mania Risperidone-acute mania Quetiapine-DSM-IV or Schizo d/o and neuroleptic dependent Ziprasidone- BDI with manic or mixed current episode Clozapine- refractory mania, ADHD diagnosis Based on DSM-IV Evaluation made on more than 1 visit Functional impariment in more than 1 setting Sx present > 6months Multiple input information, Depression ???? Dysthymia, Schizophrenia signs and symptoms Positive Sx, Lithium- the standard * rapid absorption * peak 0.25-12h * Vd = TBW * freely crosses placenta * not metabolized * t1/2 = 24h/36h (elderly) drug interactions NSAID's Thiazide diuretics ACE inhibitors, Panic Attacks criteria 4 or more Sx: - palpitations, sweating, trembling, SOB, choking, chest pain, nausea, dizzy/lightheaded derealization/depersonalization, fear of loss of control,chill / hot flashes, Atypical Agents Last resort / Resistant cases Clozapine, Schizophrenia Therapeutic goals Maintenance - Improve functioning and QOL, mainrtain baselind Fx, optimize dose/ADR, monitor for Sx of relapse, monitor ADR, Bipolar Disorders cycles of mixed Major depressive episode, Bipolar Disorders pharmacological intervention Lithium- the standard * rapid absorption * peak 0.25-12h * Vd = TBW * freely crosses placenta * not metabolized * t1/2 = 24h/36h (elderly), DSM_IV: Generalized anxiety disorder Panic disorder- with / without agoraphobia Agoraphobia- without panic disorder Phobia disorder- social / specific Obsessive /compulsive disorder Posttraumatic stress disorder Acute stress disorder ???? Panic Attacks, Non-pharnmacological- * cognitive behavioral treatment- anticipatory /uncomplicated Pharmacological- * benzodiazepines * antidepressants example benzodiazepines Alprazolam Clonazepam, DSM_IV: Generalized anxiety disorder Panic disorder- with / without agoraphobia Agoraphobia- without panic disorder Phobia disorder- social / specific Obsessive /compulsive disorder Posttraumatic stress disorder Acute stress disorder ???? Generalized Anxiety, Schizophrenia treatment Typical agents, Pharmacological: -Stimulants, TCA's, Clonidine /guanfacine stimulants Ritalin Concerta Dexadrine Adderall Cylert, Post-traumatic stress disorder criteria Confronted with event that threatened death or serious injury with intense fear/ flashbacks Flashbacks, insomnia, exaggerated startle response, Non-pharmacologic: - Psychotherapy Pharmacologic: - Antidepressants - Determined by co-morbid conditions antidepressant Tx SSRI's TCA's MAO's, Bipolar Disorders clinical course Episodes lasts weeks-months 3-10 yr between onset and presentation 90% have ɭ episode in lifetime alcohol / substance abuse is common mortality rate 2-3 x general population, Panic Attacks treatment Non-pharnmacological- * cognitive behavioral treatment- anticipatory /uncomplicated Pharmacological- * benzodiazepines * antidepressants