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This Concept Map, created with IHMC CmapTools, has information related to: neuromuscular junction, <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> <mmultiscripts> <mtext> Na </mtext> <none/> <mtext> + </mtext> </mmultiscripts> <mtext> ligand 
gated channels </mtext> </mrow> </math> and cause them to open 4. Sodium ions, cytosol of postsynaptical membrane, tropomysin to shift and thus exposing myosin binding site, presynaptic membrane releasing acetylcholine, troponin causing tropomysin, action potential 5. Action potential then spread through transverse tubule, Describe the events at the neuromuscular junction and post synaptic cell which cause skeletal muscle to contract occurs when 1. Action potential, depolarization above threshold value produces action potential 5. Action potential, sarcoplasmic reticulum and stimulates release of <math xmlns="http://www.w3.org/1998/Math/MathML"> <mmultiscripts> <mtext> Ca </mtext> <none/> <mtext> 2+ </mtext> </mmultiscripts> </math>, extracellular fluid diffuse into cytosol, calcium ions diffuse into myofibril, actin myofilament and myosin head. 7. Releasing a phosphate from ATP from myosin head, transverse tubule and reaches sarcoplasmic reticulum, powerstroke causing actin myofilament to slide past myosin myofilament, myosin binding site forming a cross-bridge, 2. Calcium ions stimulate synaptic vesicles, postsynaptical membrane causing depolarization, 4. Sodium ions from extracellular fluid, acetylcholine by exocytosis, synaptic vesicles to fuse to presynaptic membrane