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This Concept Map, created with IHMC CmapTools, has information related to: Jimmy Rogers, peripheral tissues contributing to was seen as increased androgen levels, DHEAS which was seen as increased androgen levels, Congenital Adrenal Hyperplasia as a result of the absence of negative feedback loop in the HPA Axis, leads to a buildup of 17a-hydroxyprogesterone which was seen as elevated 17-hydroxyprogesterone level, GnRH stimulation test showing that LH is within "pre-pubertal levels" following stimulation, DHEA by desmolase, leads to a buildup of 17a-hydroxyprogesterone which is shunted into the synthesis, key enzyme in the production of minerocorticoids, peripheral tissues contributing to precocious puberty, are inappropriate for his age leading to precocious puberty, Anterior Pituirtary which is normally inhibited from secreting ACTH by cortisol via the "short loop" which results, hypothalamus which is normally inhibited to secrete CRH by cortisol via the "long loop" which results, the increase in bone growth is seen in the Bone Age due to the such effects as osteoblast activation and enhanced "periosteal apposition of bone" (Endocrine Physiology, Molina) by Testosterone, responsible for the production of Androgens, growth of genitalia, deepening of the voice, hair growth in the axilla, and pubic area, bone and muscle growth of which the increase in bone growth is seen in the Bone Age, treated with glucocorticoid therapy which could help to deal with the absence of negative feedback loop in the HPA Axis, precocious puberty as a result of increased levels of androgens including weak andreogens like DHEA, DHEAS, and Androstenedione that are present in low quantities throughout developement but at higher levels can stimulate secondary sex characteristics, could lead to a deficiency of cortisol more comonly seen in patients with classical form of CAH, identified in Jimmy Rogers via the Tanner Stages which is a scale used to identify the stages of development based on the external primary and secondary sex characteristics, the increase in bone growth is seen in the Bone Age which should be closely monitored with a growth velocity chart while being treated with glucocorticoid therapy