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Aquest mapa conceptual conté informació relacionada amb: Burst, P h a g o l y s o s o m e mechanisms of killing/digestion LITIC ENZYMES, FREE RADICALS e.g., REACTIVE OXYGEN SPECIES are NO FREE RADICALS, NON FREE RADICALS e.g., REACTIVE BROMIDE SPECIES are NON FREE RADICALS, REACTIVE NITROGEN SPECIES are NON FREE RADICALS, REACTIVE NITROGEN SPECIES are FREE RADICALS, LITIC ENZYMES i.e., REACTIVE CHLORINE SPECIES are NON FREE RADICALS, REACTIVE SPECIES include REACTIVE CHLORINE SPECIES, FREE RADICALS e.g., NON FREE RADICALS e.g., NON FREE RADICALS e.g., REACTIVE OXYGEN SPECIES are FREE RADICALS, NO FREE RADICALS e.g., REACTIVE SPECIES include REACTIVE NITROGEN SPECIES, REACTIVE SPECIES Targets Fig. A simplified, idealized microbial cell is shown. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) mainly interact with thiols, metal centres and DNA. Direct DNA damage is of central importance to the antimicrobial actions of ROS, whereas RNS inhibit respiration and interfere with DNA replication through the inactivation of zinc metalloproteins., P h a g o l y s o s o m e mechanisms of killing/digestion REACTIVE SPECIES, REACTIVE SPECIES include REACTIVE OXYGEN SPECIES, REACTIVE SPECIES include REACTIVE BROMIDE SPECIES